דף הבית

קישור אקדמי

המחלקה לרפואה קרדיו-וסקולרית היא מחלקת הוראה של ביה'ס לרפואה של הטכניון ע'ש ברוס ורות רפפורט.
ההוראה כוללת למידה פרונטלית, למידה ליד מיטת החולה והוראת סטודנטים לתאר ראשון, שני ודוקטורנטים (MD, MSc, PhD).

Yuval R, Halon DA, Merdler A, Khader N, Karkabi B, Uziel K, Lewis BS: Patient comprehension and reaction to participating in a double-blind randomized clinical trial (ISIS-4)in acute myocardial infarction. Arch Intern Med, 2000;160:1142‑1146.
Halon DA, Flugelman MY, Merdler A, Rennert H, Shahla J, Lewis BS: Long-term results of coronary balloon angioplasty in unstable angina pectoris. J Clin Basic Cardiol 2000;3:99-101.
Flugelman MY, Halon DA, Fischer L, Lewis BS: Studies of atherectomy specimens in patients with acute coronary syndromes. J Clin Basic Cardiol 2000;3:91-94.
Halon DA, Merdler A, Flugelman MY, Rennert H, Weisz G, Shahla J, Lewis BS: Late-onset heart failure as a mechanism for adverse long-term outcome in diabetic patients undergoing revascularization: a 13 year report from the Lady Davis Carmel Med Center Registry. Am J Cardiol 2000;85:1420-1426.
Lewis BS, Merdler A, Halon DA, Flugelman MY: Reappraising the role of calcium antagonists in the management of patients with coronary artery disease. In Cardiovascular Pharmacotherapy, Eds. AJ Reyes, MFC Maranhao, pp. 33-38, Monduzzi Editore, Bologna, Italy, 2000.
Lewis BS, Halon DA, Karkabi B, Flugelman MY: Mega-trials of drugs for acute coronary syndromes: what have we learnt? In Cardiovascular Pharmacotherapy, Eds. AJ Reyes, MFC Maranhao, pp. 27-32, Monduzzi Editore, Bologna, Italy, 2000.
Jaffe R, Halon DA, Weisz G, Lewis BS: Pseudohypotension in a patient with malignant hypertension. IMAJ, 2000;2:484-485.
Halon DA, Merdler A, Flugelman MY, Rennert HS, Weisz G, Shahla J, Lewis BS: Similar late revascularization rates 10 to 12 years after angioplasty or bypass surgery for multivessel coronary disease: a report from the LDCMC registry. Am J Cardiol 2000;86:1131-1134.
Weisz A, Koren B, Fischer L, Lewis BS, Flugelman MY: Therapeutic angiogenesis for ischemic syndromes. IMAJ 2000;2(Suppl):52-57.

Lewis BS: Commentary on “There was no difference in major cardiac events among PTCA patients who received either iodixanol or ioxaglate”. Evidence-based Cardiovasc Med 2000;4:73.
Lewis BS, Halon DA, Shiran A, Flugelman MY, Merdler A, Khader N, Shahla J, Yuval R: New concepts and new trials of calcium antagonists for coronary artery disease. In Coronary Artery Disease - Prevention to Intervention, Eds. BS Lewis, DA Halon, MY Flugelman, P Touboul, pp. 65-71, Monduzzi, Bologna, 2000.

Halon DA, Flugelman MY, Rennert HS, Lewis BS: Long-term (15 year) outcome after myocardial by PTCA or CABG: what have we learned? In Coronary Artery Disease - Prevention to Intervention, Eds. BS Lewis, DA Halon, MY Flugelman, P Touboul, pp. 95-102, Monduzzi, Bologna, 2000.
Flugelman MY, Halon DA, Lewis, BS: Viral vectors and delivery systems for gene therapy in cardiovascular medicine - the intersection of molecular biology and interventional cardiology. In Coronary Artery Disease - Prevention to Intervention, Eds. BS Lewis, DA Halon, MY Flugelman, P Touboul, pp. 13-17, Monduzzi, Bologna, 2000.
CURE Study Investigators: The Clopidogrel in Unstable angina to Prevent Recurrent Events (CURE) trial programme. Eur Heart J, 2000;21:2033-2041.
Yuval R, Uziel K, Gordon N, Merdler A, Khader N, Karkabi B, Flugelman MY, Halon DA, Lewis BS: Perceived benefit after participating in positive and negative/neutral heart failure trials: the patients’ perspective. Eur J Heart Failure 2001;3:217-223.
Weisz A, Koren B, Cohen T, Neufeld G, Kleinberger T, Lewis BS, Flugelman MY: Increased VEGF165 binding to KDR receptor following infection of human vascular cells by recombinant adenovirus encoding the VEGF165 gene. Circulation 2001;103:1887-1892.
Yuval R, Halon DA, Lewis BS: Patients’ point of view in heart failure trials. JAMA, 2001;285:883-884.
Amir O, Merdler A, Shiran A: Bilateral atrial myxomas associated with hyperpigmented skin lesions. N Engl J Med 2001;344:938-9.
OASIS Investigators: Effects of long-term moderate intensity oral anticoagulation in addition to aspirin in unstable angina. J Am Coll Cardiol 2001;37:475-484.
The CURE investigators: Effects of clopidogrel in addition to aspirin in patients with acute coronary syndromes without ST-segment elevation. N Engl J Med 2001;345:494-502.
Lewis BS, Bolling SF: Surgical approaches to the management of heart failure. Heart Fail Rev 2001;6:161.
Mehta SR, Yusuf S, Peters RJ, Bertrand ME, Lewis BS, Natarajan MK, Malmberg K, Rupprecht H-J, Zhao F, Fox KAA: Effects of clopidogrel and aspirin pretreatment followed by long term therapy after percutaneous coronary intervention: the PCI CURE study. Lancet 2001;358:527-533.
Fischer L, Weisz A, Koren B, Halon DA, Lewis BS, Flugelman MY: Gene therapy for cardiovascular disease. In Advances in Coronary Artery Disease, Eds. BS Lewis, DA Halon, MY Flugelman, J Hradec, pp 3-12, Monduzzi Editore, Bologna, 2001.
Lewis BS, Halon DA, Flugelman MY, Jaffe R, Goldstein Y, Yuval R: Current management of acute coronary syndromes using evidence-based cardiovascular medicine. In Advances in Coronary Artery Disease, Eds. BS Lewis, DA Halon, MY Flugelman, J Hradec, pp 43-49, Monduzzi Editore, Bologna, 2001.
Halon DA, Adawi S, Meri I, Flugelman MY, Lewis BS: Acute ischemic syndromes in octogenarians - one year outcome in patients treated with a selective interventional approach. In Advances in Coronary Artery Disease, Eds. BS Lewis, DA Halon, MY Flugelman, J Hradec, pp 91-96, Monduzzi Editore, Bologna, 2001.
Shiran A, Weissman NJ, Merdler A, Karkabi B, Khader N, Aviram S, Goldstein SA, Pinnow E, Lewis BS: Transesophageal echocardiographic findings in patients with non-obstructed prosthetic valves and suspected cardiac source of embolism. Am J Cardiol 2001;88:1441-1444.
Mehta SR, Eikelboom JW, Rupprecht H-J, Lewis BS, Natarajan MK, Yi C, Pogue J, Yusuf S: Efficacy of hirudin in reducing cardiovascular events in patients with acute coronary syndromes undergoing early percutaneous coronary intervention. Eur Heart J 2002;23:117-123.
Schliamser JE, Avramovitch NA, Karkabi B, Flugelman MY, Militianu A, Lewis BS: Rhabdomyolysis induced by repeated internal cardioverter defibrillator discharges. PACE 2002;25:516-517.
Halon DA, Rennert HS, Flugelman MY, Jaffe R, Lewis BS: Burden of late repeat hospitalization and its determinants following angioplasty or bypass surgery: a long-term (13 year) report from the Lady Davis Carmel Med Center Registry. Cardiology 2002;98:67-74.
Avramovitch NA, Flugelman MY, Halon DA, Lewis BS: Bilateral coronary artery-pulmonary fistulae. IMAJ 2002;4:1162.
Jaffe R, Ben Haim S, Karkabi B, Front A, Gips S, Weisz G, Khader N, Merdler A, Flugelman MY, Halon DA, Lewis BS: Myocardial perfusion by SPECT Thallium-201 scintigraphy early (12-24h) after coronary balloon angioplasty and stenting: significance regarding late clinical outcome and need for target lesion revascularization. Cardiology 2002;98:60-66.
Avramovitch NA, Militianu A, Lewis BS: Right sided pre-pectoral implantation of an automatic implantable cardioverter defibrillator in a right pneumonectomized patient. Pacing Clin Electrophysiol 2002;25:1790-1791.
Dori G, Denekamp Y, Fishman S, Rosenthal A, Lewis BS, Bitterman H: Evaluation of the phase-plane ECG as a technique for detecting acute coronary occlusion. Int J Cardiol 2002;84:161-170.
Fischer L, Preis M, Weisz A, Koren B, Lewis BS, Flugelman MY: Viral vectors for vascular gene therapy. Exp Clin Cardiol 2002;7:106-112.
Cotter G, Cannon CP, McCabe CH, Michowitz Y, Kaluski E, Charlesworth A, Milovanov O, Bentley J, Blatt A, Krakover R, Zimlichman R, Reisin L, Marmor A, Lewis BS, Vered Z, Caspi A, Braunwald E: Prior peripheral arterial disease and cerebrovascular disease are independent predictors of adverse outcome in patients with acute coronary syndromes: are we doing enough? Am Heart J 2003;145:622-627.
Yuval R, Halon DA, Flugelman MY, Lewis BS: Perceived patient comprehension in acute and chronic clinical cardiovascular trials. Cardiology 2003;99:68-71.
Lewis BS, Yuval R, Halon DA, Flugelman MY: Selection bias introduced by the informed consent process. Lancet 2003;361:1990-1991.
Torre-Amione G, Young JB, Colucci W, Lewis BS, Pratt C, Cotter G, Stangl K, Elkayam U, Teerlink JR, Frey A, Rainisio M, Kobrin I: Hemodynamic and clinical effects of tezosentan, an intravenous dual endothelin receptor antagonist, in patients hospitalized for acute decompensated heart failure. J Am Coll Cardiol 2003;42:140-7.
Peters RJG, Mehta SR, Fox KAA, Zhao F, Lewis BS, Kopecky SL, Diaz R, Commerford PJ, Valentin V, Yusuf S, for the CURE (Clopidogrel in Unstable angina to prevent Recurrent Events) trial investigators: The effects of aspirin dose when used alone or in combination with clopidogrel in patients with acute coronary syndromes:Observations from the CURE study. Circulation 2003;108:1682-7.
Halon DA, Dobrecky-Meri I, Adawi S, Lewis BS: Outcomes of medical and interventional therapy in elderly patients with acute coronary syndromes. In Frontiers in Coronary Artery Disease, Eds. BS Lewis, DA Halon, MY Flugelman, GF Gensini, pp 575-579, Monduzzi Editore, Bologna, 2003.
Lewis BS, Yuval R, Pikan-Shalem R, Goldhammer E, Flugelman MY, HalonDA: Prevalence of heart failure in hospitalized patients in Israel: the Haifa experience. J Isr Heart Soc 2003;13:40-44.
Halon DA, Adawi S, Dobrecky-Meri I, Lewis BS: Importance of increasing age on the presentation and outcome of acute coronary syndromes in elderly patients. J Am Coll Cardiol 2004;43:346-352.
Shehadeh J, Lewis BS, Weisz G, David M, Ashkenazi T, Halon DA: Relation between C-reactive protein, treadmill exercise testing and inducible myocardial ischemia. Am J Cardiol, 2004;93:614-617.
Amir O, Alroy S, Schliamser JE, Asmir I, Shiran A, Flugelman MY, Halon DA, Lewis BS: Brachial artery endothelial function in residents and fellows working night shifts. Am J Cardiol 2004;93:947-949.
Shiran A, Lewis BS: Acquired partially flail leaflet causing severe mitral regurgitation in a congenital double-orifice mitral valve. J Am Soc Echocardiogr. 2004;17:478-479.
Rubinshtein R, Jaffe R, Flugelman MY, Karkabi B, Lewis BS: Thrombolysis in patients with a brain tumor. Heart, in press.
Dori G, Denekamp Y, Fishman S, Rosenthal A, Frajewicki V, Lewis BS, Bitterman H: Changes in the slope of the first major deflection of the ECG complex during acute coronary occlusion. Computers Biol Med, in press.
Shnaider H, Shiran A, Lorber A: Right ventricular diastolic dysfunction and patent foramen ovale causing profound cyanosis. Heart. 2004;90:e31.
Dori G, Denekamp Y, Fishman S, Rosenthal A, Frajewicki V, Lewis BS, Bitterman H: Non-invasive computerized detection of acute coronary occlusion. Med Biol Eng Comput. 2004;42:294-302.
Jaffe R, Rubinshtein R, Feigenberg Z, Talor E, Michaelson M, Halon DA, Flugelman MY, Lewis BS: Evaluation of isoproterenol in patients undergoing resuscitation for out-of-hospital asystolic cardiac arrest: the Israel resuscitation with isoproterenol study (IRIS) prospective randomized clinical trial. Am J Cardiol 2004;93:1407-9.
Flugelman MY, Lewis BS: The promise of myocardial repair towards a better understanding. Eur Heart J2004;25:1483-5.

Submitted For Publication

Jaffe R, Halon DA, Ben Haim S, Gips S, Karkabi B, Khader N, Adawi S, Front A, Shiran A, Rubinshtein R, Goldstein Y, Weiss D, Merdler A, Flugelman MY, Lewis BS: Advantage of a routine versus selective invasive strategy for identifying candidates for revascularization following low risk ST-elevation myocardial infarction: insights from the Lady Davis Carmel Medical Center (LDCMC) Registry.
Zlotnick AY, Ammar R, Gaspar T, Turgeman Y, Rosenfeld T, Peled N, Lewis BS, Aravot D: Use of high resolution multislice cardiac CT imaging to define coronary anatomy post-aortic root replacement with coronary reimplantation.
Flugelman MY, Hamm CW, Koren B, Dichek DA, Kutryk M, Halon DA, Lewis BS: Cell seeding of stents. Book chapter.
Lewis BS, Karkabi B, Jaffe R, Yuval R, Flugelman MY, Halon DA: Anemia and heart failure: statement of the problem.
Lewis BS, Mehta SR, Fox KAA, Halon DA, Zhao F, Peters RJG, Keltai M, Budaj A, Yusuf S, for the CURE investigators: Benefit of clopidogrel according to timing of percutaneous coronary intervention in patients with acute coronary syndromes: Results from the CURE study.

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